It is a common practice to use resampling methods such as the bootstrap for calculating the p-value for each test when performing large scale multiple testing. The precision of the bootstrap p-values and that of the false discovery rate (FDR) relies on the number of bootstraps used for testing...

An objective of microarray data analysis is to identify gene expressions that are associated with a disease related outcome. For each gene, a test statistic is computed to determine if an association exists, and this statistic generates a marginal p-value. In an effort to pool this information...