Searches for genes using linkage analyses with genetic markers placed across the entire human genome are hypothesis-free experiments, which represent an extreme form of multiple testing. As such, the low p-values required to obtain nominal significance make accurate diagnostics essential to...

In the presence of dependent competing risks in survival analysis, the Cox proportional hazards model can be utilised to examine covariate effects on the cause-specific hazard function for each type of failure. The method proposed by Lunn and McNeil (1995) requires data augmentation. With k...