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Time-to-event endpoints are a common outcome of interest in randomised clinical trials. The primary analysis should usually be by intention-to-treat, giving an indication of the effectiveness of the intervention in a population as a whole. However, the benefit specifically for an individual...
Persistent link: https://www.econbiz.de/10005101306
In the presence of dependent competing risks in survival analysis, the Cox proportional hazards model can be utilised to examine covariate effects on the cause-specific hazard function for each type of failure. The method proposed by Lunn and McNeil (1995) requires data augmentation. With k...
Persistent link: https://www.econbiz.de/10005053573