Due to the re-emergence of the H5N1 avian influenza virus in recent years, many public health experts believe that the world is closer to a pandemic event than at any time since the 1968 Hong Kong flu (H3N2) outbreak. Thus, governmental and private organizations have invested significant...

The efficiency and the effectiveness of supply chain networks primarily rely on facility location decisions. However, these decisions are closely related to the other supply chain management decisions, i.e., inventory management and transportation decisions. Therefore, the main goal of this...

In this thesis, we identify the critical operational characteristics for various distribution strategies, and then develop integrated distribution network design models by taking into account those operational factors. The first part of this thesis presents a crossdocking network design problem...