Social scientists commenting on developments in the life sciences have suggested that the rise of genomics in the field of human genetics does not only involve a shift in the research agenda from relatively rare monogenetic disorders to multifactorial, common diseases, but also involves a...

In this article we introduce the notion of entrenchment to conceptualize the processes in which new technological options, through the interactions between a variety of actors, become viable and established practices in society, both satisfying and modifying needs and interests. The notion of...

User involvement is assumed to be beneficial to innovation processes. Intermediary user organisations contribute to articulating societal demands for innovations. However, the learning processes inside these organisations are still not understood well. Therefore, this paper empirically...

This paper focuses on the processes and strategies of advocates and opponents in creating, maintaining and/or contesting the protective spaces in which ‘urgently needed’ but ‘risky’ pharmaceutical innovations are managed. Drawing on transition literature and recent work on niche...