Continuum and compartmental models are presented as alternative descriptions of the electrical behaviour of a dendrite. The one-dimensional continuum model provides a reference against which the accuracy of compartmental models may be assessed. Traditional compartmental models are shown to be...

Evoked potentials are usually evaluated subjectively, by visual inspection, and considerable differences between interpretations can occur. Objective, automated methods are normally based on calculating one (or more) parameters from the data, but only some of these techniques can provide...

Muscle models are an important tool in the development of newrehabilitation and diagnostic techniques. Many models have been proposed in the past, but little work has been done on comparing the performance of models. In this paper, seven models that describe the isometric force response to pulse...

Purpose: Observational studies may provide important information on the long-term effects of treatments for epilepsy, but systematic reviews of observational studies may be more prone to heterogeneity and biases. These issues were investigated in a systematic review of non-randomised add-on...

In this work we develop an approach to extracting information from neural spike trains. Using the expectation-maximization (EM) algorithm, interspike interval data from experiments and simulations are fitted by mixtures of distributions, including Gamma, inverse Gaussian, log-normal, and the...

We describe a quantitative and comparative review of a selection of European birthweight standards for gestational age for singletons, to enable appropriate choices to be made for clinical and research use. Differences between median values at term across standards in 10 regions and...

The paper investigates the problem of determining patterns of criminal behaviour from official criminal histories, concentrating on the variety and type of offending convictions. The analysis is carried out on the basis of a multivariate latent Markov model which allows for discrete covariates...

In studies of properties of queues, for example in relation to Internet traffic, a subject that is of particular interest is the ‘shape’ of service time distribution. For example, we might wish to know whether the service time density is unimodal, suggesting that service time distribution is...

We present properties of a dependence measure that arises in the study of extreme values in multivariate and spatial problems. For multivariate problems the dependence measure characterises dependence at the bivariate level, for all pairs and all higher orders up to and including the dimension...

Summary. Multivariate extreme value theory and methods concern the characterization, estimation and extrapolation of the joint tail of the distribution of a d-dimensional random variable. Existing approaches are based on limiting arguments in which all components of the variable become large at...