Showing 1 - 10 of 58
Hidden population stratification (PS) is a main concern in the analysis of case-control genetic association studies. All methods to correct for hidden PS have been focused on classical hypothesis testing, and cannot be directly applied to Bayesian analysis. In this paper, to study the impact and...
Persistent link: https://www.econbiz.de/10009023549
We consider the empirical likelihood method for estimation of distribution and quantile functions where side information is incorporated through moment conditions. We systematically study the asymptotic properties of the estimators, such as the uniform strong laws of large numbers and weak...
Persistent link: https://www.econbiz.de/10010730123
It is known that in many missing data models, for example, survival data models, some parameters are root-n estimable while the others are not. When they are, their limiting distributions are often Gaussian and easy to use. When they are not, their limiting distributions, if exists, are often...
Persistent link: https://www.econbiz.de/10010572283
Bayes factor (BF) is often used to measure evidence against the null hypothesis in Bayesian hypothesis testing. In the analysis of genome-wide association (GWA) studies, extreme BF values support the associations detected based on significant p-values. Results from recent GWA studies are...
Persistent link: https://www.econbiz.de/10009142748
Modelling of HIV dynamics in AIDS research has greatly improved our understanding of the pathogenesis of HIV-1 infection and guided for the treatment of AIDS patients and evaluation of antiretroviral therapies. Some of the model parameters may have practical meanings with prior knowledge...
Persistent link: https://www.econbiz.de/10010976112
Persistent link: https://www.econbiz.de/10010946990
Non-central chi-squared distribution plays a vital role in commonly used statistical testing procedures. The non-centrality parameter [delta] provides valuable information on the power of the associated test. In this paper, based on one observation X sampled from a chi-squared distribution with...
Persistent link: https://www.econbiz.de/10005259081
Persistent link: https://www.econbiz.de/10008591068
Missing data often arise in practice. The commonly employed approach to handle the missing data is imputation, which is effective when the missing mechanism is known and each subject in the data set misses at random. However, the situation where the imputation is not appropriate often emerged....
Persistent link: https://www.econbiz.de/10010871479
Persistent link: https://www.econbiz.de/10008452557