We study the problem of determining both the structure and the schedule of projects subject to capacity constraints. We assume that those projects are flexible in the sense that the activities to be implemented are not entirely known in advance. In such a setting, decisions must be made with...

In projects with a flexible project structure, the activities that have to be scheduled are not completely known beforehand. Instead, scheduling such a project includes the decision whether to carry out particular activities at all. This also effects precedence constraints between the finally...

We present a detailed analysis of the patient and resource scheduling problem in rehabilitation hospitals. In practice, the predominantly therapeutical treatments and activities which are prescribed for the patients are typically scheduled manually. This leads to rigid and inefficient schedules...

This paper presents a generic modeling framework to simultaneously decide about production quantities and maintenance operations for a capacitated resource facing a dynamic demand for di erent types of products. As the resource needs to be setup for each speci c type of product, a lot-sizing...

This paper treats the problem of setting the inventory level and optimizing the buffer allocation of closed-loop flow lines operating under the constant-work-in-process (CONWIP) protocol. We solve a very large but simple linear program that models an entire simulation run of a closed-loop flow...

We present a stochastic version of the single-level, multi-product dynamic lotsizing problem subject to a capacity constraint. A production schedule has to be determined for random demand so that expected costs are minimized and a constraint based on a new backlog-oriented $\delta$-service-level...

The transportation processes for patients, personnel, and material in large and complex maximum-care hospitals with many departments can consume significant resources and thus induce substantial logistics costs. These costs are largely determined by the allocation of the different departments...

This paper treats the problem of setting the inventory level of closed-loop flow lines operating under the constant-work-in-process (CONWIP) protocol. We solve a huge but simple linear program that models an entire simulation run of a closed-loop flow line in discrete time to determine a...

This paper presents an optimization-based solution approach for the dynamic multi-level capacitated lot sizing problem (MLCLSP) with positive lead times. The key idea is to solve a series of mixed-integer programs in an iterative fix-and-optimize algorithm. Each of these programs is optimized...

This paper presents a new algorithm for the dynamic Multi-Level Capacitated Lot Sizing Problem with Setup Carry-Overs (MLCLSP-L). The MLCLSP-L is a big-bucket model that allows the production of any number of products within a period, but it incorporates partial sequencing of the production...