We present solution methodologies for vehicle routing problems (VRPs) with stochastic demand, with a specific focus on the vehicle routing problem with stochastic demand (VRPSD) and the vehicle routing problem with stochastic demand and duration limits (VRPSDL). The VRPSD and the VRPSDL are...

This article explores adaptive management (AM) for decision-making under environmental uncertainty. In the context of targeting invasive species inspections of agricultural imports, I find that risk aversion increases the relative value of AM and can increase the rate of exploratory action....

The network revenue management (RM) problem arises in airline, hotel, media, and other industries where the sale products use multiple resources. It can be formulated as a stochastic dynamic program but the dynamic program is computationally intractable because of an exponentially large state...

The idea of price-directed control is to use an operating policy that exploits optimal dual prices from a mathematical programming relaxation of the underlying control problem. We apply it to the problem of replenishing inventory to subsets of products/locations, such as in the distribution of...

Analyses of global climate policy as a sequential decision under uncertainty have been severely restricted by dimensionality and computational burdens. Therefore, they have limited the number of decision stages, discrete actions, or number and type of uncertainties considered. In particular, two...

In this paper, we study a dynamic fleet management problem with uncertain demands and customer chosen service levels. We first show that the problem can be transformed into a dynamic network with partially dependent random arc capacities, and then develop a structural decomposition approach...

We study a scheduling problem in which arriving patients require appointments at specific future days within a treatment specific time window. This research is motivated by a study of chemotherapy scheduling practices at the British Columbia Cancer Agency (Canada). We formulate this problem as a...

In the controlled ovarian hyperstimulation (COH) treatment, clinicians monitor the patients’ physiological responses to gonadotropin administration to tradeoff between pregnancy probability and ovarian hyperstimulation syndrome (OHSS). We formulate the dosage control problem in the COH...