"Orson Wells made Citizen Kane, his greatest movie, when he was 25 years old; Frank Lloyd Wright designed Fallingwater, his most famous house, when he was 70. Contrasts as great as this raise the question of whether there is a general explanation of when in their lives great innovators are most...

We study targeted lockdowns in a multi-group SIR model where infection, hospitalization and fatality rates vary between groups—in particular between the “young”, “the middle-aged” and the “old”. Our model enables a tractable quantitative analysis of optimal policy. For baseline...