Background: Inborn errors of metabolism (IEM) are a significant cause of morbidity and mortality in North Africa and the Middle East. With the evident success of neighbouring countries in initiating neonatal screening for IEM, the Libyan Authorities are now considering introducing neonatal...

Objective: The objective of this study was to estimate the annual resource use and corresponding costs (at 1996/97 prices) to the UK's National Health Service (NHS) arising from the management of chronic obstructive pulmonary disease (COPD). Design and Setting: A subgroup analysis was performed...

Objective: This study estimated the cost to UK society of an annual cohort of newly diagnosed patients with schizophrenia over the first 5 years following diagnosis, using an incidence-based cost-of-illness framework. Design and setting: A discrete event model of the course of schizophrenia was...

Objective: To determine the effect of age, disease severity and compliance on the annual primary-care cost of managing patients with asthma initially on British Thoracic Society British Guidelines on Asthma Management (BGAM) treatment steps 2/3 over 5 years. Design and setting: A modelling study...

Objective: To measure health-related quality of life (HR-QOL) among a sample of men with erectile dysfunction (ED) in the UK. Study population and methods: A structured questionnaire was mailed to a sample of 5000 men in the UK with ED. The questionnaire included the International Index of...

An extensive MEDLINE search revealed a paucity of studies assessing economic outcomes associated with managing emphysema. Consequently, we estimated the annual levels of National Health Service (NHS) resource use and corresponding costs (at 1995/96 prices), by performing a subgroup analysis of a...

Objectives: To model the economic impact of introducing an occupational vaccination programme for influenza with an inactivated influenza subunit vaccine (Influvac(R)) in the UK. Design and setting: Using published sources, a decision tree was constructed which modelled the costs and benefits of...

Objective: To estimate the relative cost effectiveness for women aged =30 years, starting long-term hormonal contraception with either levonorgestrel intrauterine system (Mirena(R)), etonogestrel subdermal implant (Implanon(R)) or medroxyprogesterone acetate injection (Depo-Provera(R)). Design...

Objective: The objective of this study was to estimate the annual socioeconomic burden imposed by erectile dysfunction (ED) on UK society. Design and Setting: Health service resource use attributable to ED during 1997/1998 was obtained from appropriate databases and a panel of 22 hospital...

Objective: To estimate the annual socioeconomic burden imposed by alcohol misuse on Scottish society. Design and setting: Resource use attributable to alcohol misuse was obtained from appropriate databases, published literature and a Working Party on Social Work Caseload and Alcohol Misuse. Unit...