This report presents a computer model for evaluating the cost-effectiveness (CE) of Hormone Replacement Therapy (HRT). The model is an extension of a previous model and includes also the risk of spine and wrist fracture. New Swedish data on risk of coronary heart disease and related mortality...

The purpose of this study was to estimate the risk and mortality of breast cancer recurrences in Swedish women, and to analyse changes over time and variations between patients in different risk groups. Such estimates are of key importance for modelling the cost-effectiveness of different...

The cost-effectiveness of hormone replacement therapy (HRT) based on a societal perspective is reassessed based on new medical evidence found in the Women’s Health Initiative (WHI). Within a model framework using an individual state transition model the cost-effectiveness of 50-60 year old...

This study has used a cross-sectional, 'bottom-up' design to determine the cost to society of multiple sclerosis (MS) in Sweden in 1998. The total cost of MS was estimated at 4 868 MSEK, meaning an annual cost of 442 500 SEK per patient. Direct costs accounted for about 67% of total cost, and...

We performed a cross-sectional, “bottom-up” observational study of resource consumption and quality of life of patients with multiple sclerosis (MS) in Germany. Six centers participated in the study. Patients were asked to complete a questionnaire, and a total of 737 patients returned the...

Hälsoekonomiska utvärderingar som bedömer kostnadseffektiviteten av läkemedel blir allt vanligare inom hälso- och sjukvården som underlag för beslut om läkemedelsanvändning. Antalet publicerade hälsoekonomiska studier har ökat kraftigt från slutet av 80-talet, men fördelningen av...

There are few studies investigating the consequences of osteoporotic (low bone density) fractures in terms of costs and health outcomes. The purpose of this Swedish pilot study is to assess the costs and quality of life related to fractures of the hip, spine, wrist and shoulder and further to...

Abstract: We performed a cross-sectional, "bottom-up" observational study of resource consumption and quality of life of patients with multiple sclerosis (MS) in the United Kingdom. Three centers participated in the study. Patients received a questionnaire either by mail or during a clinic...

Background <p> Economic evaluation of treatments in multiple sclerosis (MS) presents a challenge. The disease affects a number of different body functions and leads to severe disability over time, without however a strong effect on mortality. At onset, the majority of patients will have...</p>

I denna rapport analyseras sambandet mellan priser, marknadsandelar och terapeutisk innovationshöjd för ett antal läkemedel (NCE preparat) introducerade på den svenska marknaden mellan 1987 och 2000. Det finns ett positivt samband mellan innovationshöjd och prispremier vid tidpunkten för...