Leung, Denis Heng-Yan; Wang, You-Gan; Amar, David - In: Journal of the Royal Statistical Society Series C 52 (2003) 2, pp. 139-152
Interim analysis is important in a large clinical trial for ethical and cost considerations. Sometimes, an interim analysis needs to be performed at an earlier than planned time point. In that case, methods using stochastic curtailment are useful in examining the data for early stopping while...
