Response Surface Methodology (RSM) is a tool that was introduced in the early 50's by Box and Wilson (1951). It is a collection of mathematical and statistical techniques useful for the approximation and optimization of stochastic models. Applications of RSM can be found in e.g. chemical,...

Response Surface Methodology (RSM) is a tool that was introduced in the early 50's by Box and Wilson (1951). It is a collection of mathematical and statistical techniques useful for the approximation and optimization of stochastic models. Applications of RSM can be found in e.g. chemical,...

Response Surface Methodology (RSM) is a tool that was introduced in the early 50´s by Box and Wilson (1951). It is a collection of mathematical and statistical techniques useful for the approximation and optimization of stochastic models. Applications of RSM can be found in e.g. chemical,...

Response Surface Methodology (RSM) is a tool that was introduced in the early 50's by Box and Wilson (1951). It is a collection of mathematical and statistical techniques useful for the approximation and optimization of stochastic models. Applications of RSM can be found in e.g. chemical,...

Response Surface Methodology (RSM) is a tool that was introduced in the early 50's by Box and Wilson (1951). It is a collection of mathematical and statistical techniques useful for the approximation and optimization of stochastic models. Applications of RSM can be found in e.g. chemical,...