We focus on the D-optimal design of screening experiments involving main-effects regression models, especially with large numbers of factors and observations. We propose a new selection strategy for the coordinate-exchange algorithm based on an orthogonality measure of the design. Computational...

In this paper we defi?ne a new problem, the aim of which is to fi?nd a set of k dissimilar alternative solutions for a vehicle routing problem (VRP) on a single instance. ?This problem has several practical applications in the cash-in-transit sector and in the transportation of hazardous...