For modern evidence-based medicine, decisions on disease prevention or management strategies are often guided by a risk index system. For each individual, the system uses his/her baseline information to estimate the risk of experiencing a future disease-related clinical event. Such a risk...

When the estimating function for a vector of parameters is not smooth, it is often rather difficult, if not impossible, to obtain a consistent estimator by solving the corresponding estimating equation using standard numerical techniques. In this paper, we propose a simple inference procedure...