Biologicals are the fastest growing segment of the global pharmaceutical market, reaching 199 billion USD sales per year with 9.8% 10-year compound annual growth rate (CAGR). Being less costly, yet equally efficacious and safe alternatives to originator reference products, biosimilars drive...

Introduction: Early biological treatment of rheumatoid arthritis (RA) may reverse the autoimmune response in some patients resulting in favorable long-term outcomes. Although the cost-effectiveness of this strategy has been questioned, biosimilar entries warrant the revision of clinical and...

Purpose The CarerQol instrument has been designed and validated as an instrument able to measure both the positive and the negative impacts of caregiving on the quality of life of informal caregivers (CarerQol-7D), as well as their general happiness (CarerQol-VAS). The aim of this study was to...

OBJECTIVES: PAM-13 is a measure of the knowledge, skill, and confidence for managing one’s own health. We developed the Hungarian version of the PAM-13 instrument and tested its psychometric properties. METHODS: In linguistic adaptation and psychometric testing, we followed the WHO and COSMIN...

Background We aimed to determine the acceptability of non-perfect health states with age using the EQ VAS and analyse the infuencing factors. Methods We conducted a cross-sectional survey on a convenience sample from the general population (N=200). Respondents were asked to indicate on the EQ...

Abstract Background EQ-5D-3L population data are available only from Hungary, Poland and Slovenia in Central and Eastern Europe (CEE). We aimed to compare the accessible studies and estimate a regional EQ-5D-3L population norm for CEE. Methods A combined dataset using patient-level data of 8850...

Background In the Central and Eastern European region, the British EQ-5D-3L value set is used commonly in quality of life (QoL) studies. Only Poland and Slovenia have country-specifc weights. Our study aimed to investigate the impact of value set choice on the evaluation of 18 chronic conditions...

Background We adapted the eHealth Literacy Scale (eHEALS) for Hungary and tested its psychometric properties on a large representative online sample of the general population. Methods The Hungarian version of eHEALS was developed using forward–backward translation. For the valuation study,...

Background We aimed to investigate individuals’ subjective expectations regarding health and happiness alongside their provisions on life circumstances for older ages. Methods A cross-sectional online survey was performed involving a representative sample (N=1000; mean age 50.9, SD=15.4; female...

Background We aimed to investigate the burden of informal care in Hungary (HU), Poland (PL) and Slovenia (SI). Methods A cross-sectional online survey was performed involving representative samples of 1000 respondents per country. Caregiving situations were explored; health status of informal...