Beginning in the United States in December 2007, and with much greater intensity since September 2008, much of the industrialised world is being subjected to an economic downturn, which manifests in unemployment, small-business lending, and in particular, the closing of small business...

In case–control studies of gene-environment association with disease, when genetic and environmental exposures can be assumed to be independent in the underlying population, one may exploit the independence in order to derive more efficient estimation techniques than the traditional logistic...

We consider the inference problem of estimating covariate and genetic effects in a family-based case-control study where families are ascertained on the basis of the number of cases within the family. However, our interest lies not only in estimating the fixed covariate effects but also in...

With the deregulation of the electric power market in New England, an independent system operator (ISO) has been separated from the New England Power Pool (NEPOOL). The ISO provides a regional spot market, with bids on various electricity-related products and services submitted by utilities and...

Genetic association studies aim to detect association between one or more genetic polymorphisms and complex traits, which might be some quantitative characteristic or a qualitative attribute of disease. In Chapter 1, we introduce the development of methods for association mapping in the past...