Objectives: The purpose of this study was to develop and validate an algorithm that predicts EQ-5D utility from the St. George's Respiratory Questionnaire (SGRQ) in subjects with chronic obstructive pulmonary disease and to examine the effect of using this algorithm in predicting...

TORCH was a 3 year multi-centre trial of 6112 patients randomized to: salmeterol (SAL), fluticasone propionate (FP), the FP+SAL combination (SFC), or placebo (PL). Here we assess the cost-effectiveness of treatments evaluated in the TORCH study. Three year all-cause hospitalization, medication,...

Rational choice analysis of collective action predicts that individual members of a large group will not contribute voluntarily towards a common cause; members of large groups attribute no significance to individual action. Large groups are mobilised by the attraction of private goods and...