Evaluation of hazards associated with exposure to chemicals, understanding of relationships between dose and adverse effect, extrapolation of effects from high experimental doses to low doses associated with actual exposures, and extrapolation from effects observed in animals to effects expected...

The expanding availability of protein data enforces the application of empirical methods necessary to recognize protein structures. In this paper a sequence-structure alignment method is described and applied to various Ubiquitin-like folded Ras-binding domains. On the basis of two probability...