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Intellectual property rights and the evergreening of pharmaceuticals

Boscheck, Ralf - In: Intereconomics 50 (2015) 4, pp. 221-226

exclusivity for pharmaceuticals products and evaluates safeguards against such evergreening. …

Persistent link: https://www.econbiz.de/10011773251

Determinants of pharmaceutical innovation: The role of technological opportunities revisited

Rake, Bastian - 2012

pharmaceuticals. At the same time many scholars point out the importance of of scientific advances for the industry's R&D activities … number of new pharmaceuticals in the United States. Technological opportunities are operationalized as growth rates of the …-maximum likelihood estimator. The results reveal a rather robust and significantly positive response of the number of new pharmaceuticals …

Persistent link: https://www.econbiz.de/10010291820

The singularity of the efficiency bound of the mixed proportional hazard model

Ridder, Geert; Woutersen, Tiemen - 2001

We reconsider the efficiency bound for the semi-parametric Mixed Proportional Hazard (MPH) model with parametric baseline hazard and regression function. This bound was first derived by Hahn (1994). One of his results is that if the baseline hazard is Weibull, the efficiency bound is singular,...

Persistent link: https://www.econbiz.de/10010291982

The singularity of the information matrix of the mixed proportional hazard model

Ridder, Geert; Woutersen, Tiemen - 2002

Elbers and Ridder (1982) identify the Mixed Proportional Hazard model by assuming that the heterogeneity has finite mean. Under this assumption, the information matrix of the MPH model may be singular. Moreover, the finite mean assumption cannot be tested. This paper proposes a new...

Persistent link: https://www.econbiz.de/10010292025

Technology shocks, employment, and labor market frictions

Mandelman, Federico S.; Zanetti, Francesco - 2008

Recent empirical evidence suggests that a positive technology shock leads to a decline in labor inputs. However, the standard real business cycle model fails to account for this empirical regularity. Can the presence of labor market frictions address this problem without otherwise altering the...

Persistent link: https://www.econbiz.de/10010292305

Learning, adaptive expectations, and technology shocks

Huang, Kevin X. D.; Liu, Zheng; Zha, Tao - 2008

This study explores the macroeconomic implications of adaptive expectations in a standard real business cycle model. When rational expectations are replaced by adaptive expectations, we show that the self-confirming equilibrium is the same as the steady-state rational expectations equilibrium...

Persistent link: https://www.econbiz.de/10010292324

Social experiments and instrumental variables with duration outcomes

Abbring, Jaap; van den Berg, Gerard - 2005

This paper examines the empirical analysis of treatment effects on duration outcomes from data that contain instrumental variation. We focus on social experiments in which an intention to treat is randomized and compliance may be imperfect. We distinguish between cases where the treatment starts...

Persistent link: https://www.econbiz.de/10010293007

Technological progress under learning by imitation

Kelly, Morgan - 2005

We analyse technological progress when knowledge has a large tacit component so that transmission of knowledge takes place through direct personal imitation. It is shown that the rate of technological progress depends on the number of innovators in the same knowledge network. Assuming the...

Persistent link: https://www.econbiz.de/10010293845

A nonparametric test for seasonal unit roots

Kunst, Robert M. - 2009

We consider a nonparametric test for the null of seasonal unit roots in quarterly time series that builds on the RUR (records unit root) test by Aparicio, Escribano, and Sipols. We find that the test concept is more promising than a formalization of visual aids such as plots by quarter. In order...

Persistent link: https://www.econbiz.de/10010294023

Carbon taxes, path dependency and directed technical change: Evidence from the auto industry

Aghion, Philippe; Dechezleprêtre, Antoine; Hemous, David; … - 2012

Can directed technical change be used to combat climate change? We construct new firm-level panel data on auto industry innovation distinguishing between dirty (internal combustion engine) and clean (e.g. electric and hybrid) patents across 80 countries over several decades. We show that firms...

Persistent link: https://www.econbiz.de/10010294270

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