Economic evaluation in modern health care systems is seen as a transparent scientific framework that can be used to advance progress towards improvements in population health at the best possible value. Despite the perceived superiority that trial-based studies have in terms of internal...

Background: As a direct result of the population growing older the total number of chronic illnesses increases. The future expenditure for care of chronically ill patients is an ever-present challenge for the health care system. New solutions based on integrated care or the inclusion of...

Background: Rotavirus gastroenteritis (RVGE) is a frequent disease in young children. The recommended German paediatric immunisation schedule does not currently include rotavirus vaccination. A lack of economic data on the impact of routine vaccination is stated as one of the reasons. As a...

Biologic drugs, as with all other medical technologies, are subject to a number of regulatory, marketing, reimbursement (financing) and other demand-restricting hurdles applied by healthcare payers. One example is the routine use of cost-effectiveness analyses or health technology assessments to...

An increasing number of primary prevention programs aimed at promoting physical exercise in children and adolescents are being piloted. As resources are limited, it is important to ascertain the costs and benefits of such programs. The aim of this systematic review is to evaluate the currently...

Background: In the face of a growing number of older adults in the population, policy-makers in high-income countries are seeking new ways to reduce the expected growth in long-term care expenditure. Research shows that disability is an important determinant of long-term care utilization. In...

Aim: To carry out a systematic review of studies that have conducted economic evaluations on smoking relapse prevention interventions by critically appraising the quality of the methodology. Methods: All relevant articles were identified by searching three electronic databases MEDLINE, EMBASE,...

We introduce a methodology for dynamic modelling and forecasting of realized covariance matrices based on generalization of the heterogeneous autoregressive model (HAR) for realized volatility. Multivariate extensions of popular HAR framework leave substantial information unmodeled in residuals....

This paper presents a brief literature review concerning the costs and benefits of electric vehicles and hybrid electric vehicles, highlighting their advantages in terms of greenhouse gas emissions reductions. Even though electric and electro-hybrid vehicles must still overcome many cultural and...

Our contribution aims to explore the different ways in which early economic data can inform public health policy decisions on new medical technologies. Methods: A broad explorative literature research was conducted to detect methodological contributions covering the health policy perspective....