We study an important problem faced by Blood Centers, of selecting screening tests for donated blood to reduce the risk of “transfusion-transmitted infectious diseases” (TTIs), including the human immunodeficiency virus (HIV), hepatitis viruses, human T-cell lymphotropic virus, syphilis,...

In this paper, we focus on a useful modeling concept that is frequently ignored while formu lating discrete optimization problems. Very often, there exists a natural symmetry inherent in the problem itself that, if propagated to the model, can hopelessly mire a branch-and-bound solver by...