In existing AS/RS research, storage assignment policies are evaluated based on the probability that item type j will be stored (and subsequently retrieved). This note applies the turnover-based and class-based assignment policies of Hausman et al. (1976) to a stochastic environment by...

We consider the problem of designing a multivehicle automated guided vehicle system (AGVS) to supplement an existing nonautomated material handling system. The AGVS consists of a pool of vehicles that deliver raw components from a central storage area to workcenters throughout the factor floor....

This paper analyzes the costs and benefits of screening women of childbearing age for HIV. The analysis is based on a dynamic compartmental model of the HIV epidemic that incorporates disease transmission and progression over time, behavioral changes, and effects of screening and associated...

We assess the cost-effectiveness of maintenance treatment for heroin addiction, with emphasis on its role in preventing HIV infection. The analysis is based on a dynamic compartmental model of the HIV epidemic among a population of adults, ages 18 to 44. The population is divided into nine...

We present a survey of over 50 representative problems in location research. Our goal is not to review all variants of different location models or to describe solution results, but rather to provide a broad overview of major location problems that have been studied, indicating briefly how they...

Currently available medication for treating many chronic diseases is often effective only for a subgroup of patients, and biomarkers accurately assessing whether an individual belongs to this subgroup do not exist. In such settings, physicians learn about the effectiveness of a drug primarily...

What happens within the university-based research enterprise when a federal funding agency abruptly changes research grant funding levels, up or down? We use simple difference equation models to show that an apparently modest increase or decrease in funding levels can have dramatic effects on...