Xiao, Yuanyuan; Segal, Mark; Yang, Yee Hwa - In: Statistical Applications in Genetics and Molecular Biology 4 (2007) 1, pp. 4-4
amounts and types of such variations are observed in different arrays. Although various normalization methods have been … for different arrays and data sets. To address this issue, we present a novel normalization technique, STEPNORM, for data …-dependent and adaptive normalization of two-channel spotted microarrays. STEPNORM performs a stepwise interrogation of a range of …