A model of early metastatic process is based on the role of the protein PAI-1, which at high enough extracellular concentration promotes the transition of cancer cells to a state prone to migration. This transition is described at the single cell level as a bi-stable switch associated with a...

The influence of the network topology on the dynamics of systems of coupled excitable units is studied numerically and demonstrates a lower dynamical variability for power-law networks than for Poisson ones. This effect which reflects a robust collective excitable behavior is however lower than...

We investigate the stationary nonequilibrium states of a quasi one-dimensional system of heavy particles whose interaction is mediated by purely elastic collisions with light particles, in contact at the boundary with two heat baths with fixed temperatures T+ and T-. It is shown that Fourier law...

Chromatin is a complex of DNA and specific proteins forming an intermediary level of organization of eukaryotic genomes, between double-stranded DNA and chromosome. Within a generic modeling of chromatin assembly, we investigate the interplay between the mechanical properties of the chromatin...