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We propose tests for equality of treatment effects in the context of a double-blind 2 x 2 cross-over trial which do not require treatment codes to be unblinded and thus can be used as a part of the interim analyses. We first discuss the set-up of a 2 x 2 cross-over trial and state the important...
Persistent link: https://www.econbiz.de/10010727901
Quality of decisions in inventory management problems depends on accuracy of parameter estimates used for decision making. In many situations, error in decision making is unavoidable. In such cases, understanding sensitivity of objective function to sub-optimal decisions is necessary for better...
Persistent link: https://www.econbiz.de/10010705920
In this paper, we examine the possibility of quickly deciding whether or not an instance of a binary knapsack problem is difficult for branch and bound algorithms. We first observe that the distribution of the objective function values is smooth and unimodal. We define a measure of difficulty of...
Persistent link: https://www.econbiz.de/10008801957
We propose a penalized splines based method to predict the pathological stage of localized prostate cancer. A combination of prostate specific antigen, Gleason histological score, and clinical stage from a cohort study of 834 prostate cancer patients are used to build the penalized splines...
Persistent link: https://www.econbiz.de/10008802058
Quality of decisions in inventory management models depends on the accuracy of parameter estimates used for decision making. In many situations, error in decision making is unavoidable. In such cases, sensitivity analysis is necessary for better implementation of the model. Though the newsvendor...
Persistent link: https://www.econbiz.de/10011097787
The two-sample problem and its extension to the <italic>k</italic>-sample problem are well known in the statistical literature. However, the discrete version of the <italic>k</italic>-sample problem is relatively less explored. Here in this work we suggest a <italic>k</italic>-sample non-parametric test procedure for discrete distributions based...
Persistent link: https://www.econbiz.de/10010976083
For stationary time series of nominal categorical data or ordinal categorical data (with arbitrary ordered numberings of the categories), autocorrelation does not make much sense. Biswas and Guha (J Stat Plan Infer 139:3076–3087, <CitationRef CitationID="CR5">2009a</CitationRef>) used mutual information as a measure of association and...</citationref>
Persistent link: https://www.econbiz.de/10010994246
In this article, a new kind of stationary zero-inflated Pegram's operator based integer-valued time series process of order p with Poisson marginal or ZIPPAR(p) is constructed for modelling a count time series consisting a large number of zeros compared to standard Poisson time series processes....
Persistent link: https://www.econbiz.de/10010855146