We study the location-inventory problem in three-level supply networks. Our model integrates three decisions: the distribution centers location, flows allocation, and shipment sizes. We propose a nonlinear continuous formulation, including transportation, fixed, handling and holding costs, which...

In recent years, it has become widely accepted that optimal supply chain design depends on the type of product the chain is catering to. Moreover, as opposed to carrying one product type only, firms deliver a variety of both functional and innovative products in parallel, complicating...

In this paper, we present a bounding methodology that allows to compute a tight lower bound on the cycle time of fork--join queueing networks with blocking and with general service time distributions. The methodology relies on two ideas. First, probability masses fitting (PMF) discretizes the...

A new alternative in the analysis of manufacturing systems with finite buffers is presented. We propose and study a new approach in order to build tractable phase-type distributions, which are required by state-of-the-art analytical models. Called "probability masses fitting" (PMF), the approach...

In health care system, the operating theatre is recognized as having an important role, notably in terms of generated income and cost. Its management, and in particular its scheduling, is thus a critical activity, and has been the sub ject of many studies. However, the stochasticity of the...