This paper examines the optimal production lot size decisions for clinical trial supply chains. One unique aspect of clinical trial supply chains is the risk of failure, meaning that the investigational drug is proven unsafe or ineffective during human testing and the trial is halted. Upon...

Component commonality has been widely recognized as a key factor in achieving product variety at low cost. Yet the theory on the value of component commonality is rather limited in the inventory literature. The existing results were built primarily on single-period models or periodic-review...

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We study the safety stock positioning problem in single-product multistage supply chains with tree network structures, where each stage controls its inventory using an installation continuous-time base-stock policy. External demands follow independent Poisson processes, and unsatisfied demands...

We consider a multi-product and multi-component Assemble-to-Order (ATO) system where the external demand follows compound Poisson processes and component inventories are controlled by continuous-time batch ordering policies. The replenishment lead-times of components are stochastic, sequential...

In many industries, customers are offered free shipping whenever an order placed exceeds a minimum quantity specified by suppliers. This allows the suppliers to achieve economies of scale in terms of production and distribution by encouraging customers to place large orders. In this paper, we...