Case-control association studies using unrelated cases and controls may suffer from potential confounding due to population stratification. Bias and variance distortion caused by population stratification in the commonly used allele-based tests can considerably inflate the Type I error rate. It...

This note develops modifications of the chi-square and maximum likelihood tests for the homogeneity of the success probabilities pi of k binomial variables when the number of trials, ni, vary widely and all pi are small. With N = [Sigma]ni, and letting the ni/N approach fixed fractions, [gamma]i...

After expressing the Fisher information in randomly censored data in terms of hazard rates, we examine the loss of Fisher information under the Koziol-Green random censoring model. Because the same parameter enters both the survival and censoring distributions in this model, the censored data...

We present a modification of a recently proposed test of symmetry about a known center. The new test uses Wilcoxon scores to weigh the runs and has a limiting normal distribution under the null hypothesis. A Monte Carlo study shows that it is more powerful than both the runs and Wilcoxon...