The results suggest that trastuzumab as adjuvant therapy for early breast cancer may be cost effective when given over either 52 or 9 weeks at current acquisition costs in Australia. However, the overall budget impact of the 52-week course is significant, and the 9-week course appears...

We present a model of a two-step solar process for producing Zn from ZnO. The process consists of the following reactions: Fe3O4(1) → 3FeO(1) + 12O2 and 3FeO(s,1) + ZnO(s) → Fe3O4(s) + Zn(g). The rate and extent of decomposition of the first reaction is limited by the rate at which O2...

This report presents the consensus recommendations of an international expert panel on indicators for patient safety. Using a structured review process, the panel set out to select indicators to cover the five key areas: areas hospital-acquired infections, sentinel events, operative and...

Medical practice variation is extensive and well documented, particularly for surgical interventions, and raises important questions for health policy. To date, however, little work has been carried out on interpractitioner variation in prescribing activity in the primary care setting. An...