Работа посвящена оценке эффективности различных программ обследования индивидуумов, предрасположенных к развитию колоректального рака, с помощью...

Статья посвящена вопросам разработки маркетинговой стратегии страховой компании с использованием основных средств математического моделирования структуры....

Among an infinite number of possible folds, nature has chosen only about 1000 distinct folds to form protein structures. Theoretical studies suggest that selected folds are intrinsically more designable than others; these selected folds are unusually stable, a property called the designability...

We investigate the evolution of asexual populations subject to a large supply of deleterious mutations such that Muller's ratchet operates. In this regime, the accumulation of deleterious mutations takes place continuously with the resulting loss of the least-loaded class of individuals. In the...

Adaptation of populations takes place with the occurrence and subsequent fixation of mutations that confer some selective advantage to the individuals which acquire it. For this reason, the study of the process of fixation of advantageous mutations has a long history in the population genetics...

The properties of the underdamped Josephson junction subjected to colored noises were investigated with large and small phase difference (φ). For the case of the large φ, we found numerically that: (i) the probability distribution function of φ exhibits monostability → bistability →...

Boolean networks with canalizing functions are used to model gene regulatory networks. In order to learn how such networks may behave under evolutionary forces, we simulate the evolution of a single Boolean network by means of an adaptive walk, which allows us to explore the fitness landscape....