The portfolio approach of financing drug development has been proposed as a financial innovation to improve the risk/return tradeoff of investment in drug development projects through the use of diversification and securitization. By investing in a sizable and well-diversified portfolio of novel...

The frequency of viral outbreaks and pandemics in the last two decades, including the current COVID pandemic, has focussed attention on Canada’s pandemic preparedness generally and its pandemic vaccine development and production self-sufficiency, in particular. As Canada faced disruptions in...

Using recent data on the unvaccinated across U.S. states, this paper focuses on the determinants of vaccine hesitancy related to the COVID-19 pandemic. Results show that more prosperous states and states with more elderly and physicians have lower vaccine hesitancy. There was some evidence of...

The emergence of Covid-19 has affected all aspects of human life across the globe. Lockdowns everywhere are having dramatic social and economic consequences. No therapy has yet been approved, and vaccines are a priority potential tool to control the pandemic and its impacts. Multiple vaccines...

Previous research has documented lower vaccination rates among ethnic and racial minorities as well as foreign-born people, thus raising concerns about health inequities during pandemics. We analyzed influenza vaccination rates among children with US-born parents and those with at least one...

We show that the anticipation of COVID-19 vaccines reduces voluntary social distancing. In a large-scale preregistered survey experiment with a representative sample, we study whether providing information about the safety, effectiveness, and availability of COVID- 19 vaccines affects compliance...

We evaluate the impact of government mandated proof of vaccination requirements for access to public venues and non-essential businesses on COVID-19 vaccine uptake. We find that the announcement of a mandate is associated with a rapid and significant surge in new vaccinations (more than 60%...

We study the role of media reporting of alleged adverse effects of influenza vaccination on adults' (aged 50 or more) decisions to vaccinate against the flu. We exploit the diffusion of news linking suspected deaths to the vaccine, during the 2014 vaccination campaign in Italy. Using daily...

We analyze the effects of a vaccination program providing free flu vaccine to individuals aged 65 or more on take-up behavior and hospitalization. Using both administrative and survey data, we implement a regression discontinuity design around the threshold at age 65, and find that the effect of...