Worldwide 10-20% of children and adolescents experience mental disorders. Mental disorders, if remain untreated, can impose enormous and lifelong burden to the individual, family and society. Yet, a large proportion of affected children do not receive treatment owing to poor accessibility to...

Screening programs for sickle cell disease, when effective, can reduce morbidity and mortality as a direct consequence of patient education and optimized clinical management. However, informed patient or parental consent is necessary prior to the screening process as a person's sickle status is...

Objective: To investigate the effect of an asthma care support program for patients under the age of 18 years. Study design: A 1 Patient groups: 318 asthma care support program participants and 318 matched non-participants. Main outcome measures: The rates of medical service utilization...

Objective: To estimate the pharmacoeconomic impact for the French Social Security System of preventing recurrent acute rhinopharyngitis (RARP) in at-risk children with OM-85 BV, an immunostimulating agent indicated for the prevention of recurrences. Design: A decision-analysis model. The...

Objective: To assess parental willingness to pay (WTP) for a shorter course of antibacterial treatment versus conventional antibacterial therapy for acute otitis media (AOM). Methods: The study population consisted of 562 parents of children who had been seen and treated by a paediatrician for...

Aim: To determine the economic impact (cost-benefit analysis) of childhood varicella vaccination, with the Oka/Merck varicella zoster virus vaccine live (Varivax(R)) in Italy. Methods: This analysis is based on an epidemiological model of varicella zoster virus (VZV) dynamics adapted to the...

Background:Background: Underuse of controller therapy among Medicaid-enrolled children is common and leads to more emergency department (ED) visits and hospitalizations. However, there is little evidence about the relationship between medication adherence, outcomes and costs once controller...

Background:Background: Attention-deficit hyperactivity disorder (ADHD) is a common psychiatric disorder in childhood, affecting 3-7% of school-age children in the US and imposing substantial economic burden. Stimulants are considered first-line pharmacological treatment and are the most...

Background and Objectives:Background and Objectives: The aim of this study was to test the feasibility of estimating preference weights for all health states defined by the Child Health Utility 9D (CHU9D), a new generic measure of health-related quality of life for children aged 7-11 years. The...

Background:Background: Cost-effectiveness analysis of pharmaceutical and other treatments for children with autism spectrum disorders (ASDs) has the potential to improve access to services by demonstrating the value of treatment to public and private payers, but methods for measuring QALYs in...