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Management of Community-Acquired Pneumonia: Defining the Role of Azithromycin
Gunasekara, Nishan S.; Barman Balfour, Julia A. - In: Disease Management and Health Outcomes 5 (1999) 1, pp. 41-54
Community-acquired pneumonia (CAP) is a common cause of morbidity and mortality and is associated with the consumption … erythromycin and clarithromycin, which require a longer treatment duration. However, the potential for prolonged subinhibitory … pharmacokinetic drug interactions than erythromycin or clarithromycin. According to US prescribing information, orally administered …
Persistent link: https://www.econbiz.de/10005590122
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Management of Acute Otitis Media: Defining the Role of Cefuroxime Axetil
Lamb, Harriet M.; Spencer, Caroline M. - In: Disease Management and Health Outcomes 8 (2000) 6, pp. 337-353
Growing concern about the rapid emergence of penicillin-resistant Streptococcus pneumoniae, as well as beta … example is the recommendations of the US Drug-Resistant S. pneumoniae (DRSP) Therapeutic Working Group which advocate an …: Cefuroxime axetil is one of very few oral agents which has proven clinical efficacy against S. pneumoniae, as well as beta …
Persistent link: https://www.econbiz.de/10005404604
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Management of HIV-1 Infection in Children: Special Considerations
Brady, Michael T. - In: Disease Management and Health Outcomes 4 (1998) 2, pp. 73-91
Optimal management of human immunodeficiency virus type 1 (HIV-1)-infected children requires a commitment from the healthcare delivery system, healthcare providers, and affected families and caregivers. When adequate resources are available (as in most industrialised nations), an aggressive...
Persistent link: https://www.econbiz.de/10005448902
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Measuring Quality of Life in Paediatric Patients
Connolly, Melinda A.; Johnson, Jeffrey A. - In: PharmacoEconomics 16 (1999) 6, pp. 605-625
The purpose of this paper is to highlight important considerations in the measurement of health-related quality of life (HR-QOL) in paediatric populations. Considerations specific to the evaluation of HR-QOL in children include children's understanding of the questions being asked, their...
Persistent link: https://www.econbiz.de/10005590507
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A Willingness-To-Pay Assessment of Parents' Preference for Shorter Duration Treatment of Acute Otitis Media in Children
Gueylard Chenevier, Delphine; LeLorier, Jacques - In: PharmacoEconomics 23 (2005) 12, pp. 1243-1255
Objective: To assess parental willingness to pay (WTP) for a shorter course of antibacterial treatment versus conventional antibacterial therapy for acute otitis media (AOM). Methods: The study population consisted of 562 parents of children who had been seen and treated by a paediatrician for...
Persistent link: https://www.econbiz.de/10005243164
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The Generation Gap: Differences Between Children and Adults Pertinent to Economic Evaluations of Health Interventions
Keren, Ron; Pati, Susmita; Feudtner, Chris - In: PharmacoEconomics 22 (2004) 2, pp. 71-81
Differences between children and adults have both technical and ethical implications for the design, interpretation and employment of economic analyses of health-related programmes. Even though policy makers increasingly turn to economic analyses to inform decisions about resource allocation,...
Persistent link: https://www.econbiz.de/10005590364
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Management Strategies for Ensuring Adequate Analgesia in Children
Lux, Melanie; Algren, Chris L.; Algren, John T. - In: Disease Management and Health Outcomes 6 (1999) 1, pp. 37-47
Pain is a complex phenomenon. Ensuring adequate analgesia in children presents a challenge for paediatric healthcare providers. Multiple factors, including cognitive, emotional, environmental, cultural and behavioural, influence the child's pain perception. Anxiety and fear compound the...
Persistent link: https://www.econbiz.de/10005590193
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Sickle Cell Disease Screening Programs: Integration Into Managed Care
Davies, Sally C.; Oni, Lola - In: Disease Management and Health Outcomes 9 (2001) 6, pp. 295-304
Screening programs for sickle cell disease, when effective, can reduce morbidity and mortality as a direct consequence of patient education and optimized clinical management. However, informed patient or parental consent is necessary prior to the screening process as a person's sickle status is...
Persistent link: https://www.econbiz.de/10005242993
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Prevention of Recurrent Rhinopharyngitis in At-Risk Children in France: A Cost-Effectiveness Model for a Nonspecific Immunostimulating Bacterial Extract (OM-85 BV)
Pessey, Jean-Jacques; Megas, Francoise; Arnould, Benoit; … - In: PharmacoEconomics 21 (2003) 14, pp. 1053-1068
Objective: To estimate the pharmacoeconomic impact for the French Social Security System of preventing recurrent acute rhinopharyngitis (RARP) in at-risk children with OM-85 BV, an immunostimulating agent indicated for the prevention of recurrences. Design: A decision-analysis model. The...
Persistent link: https://www.econbiz.de/10005243125
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The Economics of Hepatitis B Virus Vaccination: An Analysis of Cost-Effectiveness Results for Switzerland
Zurn, Pascal; Carrin, Guy; Danthine, Jean-Pierre; … - In: Disease Management and Health Outcomes 7 (2000) 6, pp. 331-347
Objective: To assess and compare the costs and effectiveness of different vaccination strategies against hepatitis B in Switzerland. Design: A birth cohort of 85 000 individuals was followed over their lifetime, using a decision-tree analysis. Published data were used to simulate the risk of...
Persistent link: https://www.econbiz.de/10005448762