With new tests being developed and marketed, the comparison of the diagnostic accuracy of two continuous-scale diagnostic tests are of great importance. Comparing the partial areas under the receiver operating characteristic curves (pAUC) is an effective method to evaluate the accuracy of two...

Let T1 and T2 be the survival times of patients randomized to, respectively, two treatment groups. The probability P(T1T2) may be used as a measure on the effect of treatments in a randomized clinical trial. With potentially censored data observed and assuming that the density functions of...

The Youden index is a widely used measure in the framework of medical diagnostic, where the effectiveness of a biomarker (screening marker or predictor) for classifying a disease status is studied. When the biomarker is continuous, it is important to determine the threshold or cut-off point to...