Showing 1 - 10 of 49
Background and Objective: A growing body of literature on the economics of depression concludes that this illness has an enormous impact on workplace performance. In addition to work cutback and sporadic absenteeism, the symptoms of depression also result in elevated rates of chronic absenteeism...
Persistent link: https://www.econbiz.de/10005404733
Chronic disease and collaboration (people The aim of this article is to outline four approaches to collaboration - epidemiologically focused collaborations, research-based consortiums, organizational-change collaborations, and patient-focused disease management strategies - currently employed to...
Persistent link: https://www.econbiz.de/10005404738
Objective: The objective of this study was to examine the cost effectiveness of fluvoxamine compared with tricyclic antidepressants (TCAs) in the treatment of patients with depressive episodes. Design and Setting: A Markov process model was constructed to model the effectiveness, as measured by...
Persistent link: https://www.econbiz.de/10005404792
Objective: To estimate the cost effectiveness of representatives of three different classes of antidepressants used in major depression in the UK NHS. Design, patients and interventions: A decision-tree model for the treatment of major depression was constructed by interviewing UK GPs and...
Persistent link: https://www.econbiz.de/10005404795
In a double-blind study in a primary-care setting in France, outpatients fulfilling DSM IV criteria for a major depressive episode were randomised to receive sertraline (50 to 150 mg/day; n = 122) or fluoxetine (20 to 60 mg/day; n = 120). Assessments, including clinical evaluation...
Persistent link: https://www.econbiz.de/10005404832
A comprehensive, multinational literature search was conducted of all articles published from 1993 to 2003 regarding the cost effectiveness of antidepressant drugs, with special emphasis on comparing third-generation antidepressants (TGAs) with tricyclic antidepressants (TCAs) and selective...
Persistent link: https://www.econbiz.de/10005404934
Worldwide, major depression is the leading cause of years lived with a disability, and the fourth cause of disability-adjusted life years. Depression is second only to hypertension as the most common chronic condition encountered in general medical practice. Unfortunately, despite the high...
Persistent link: https://www.econbiz.de/10005404970
Background: Conservative estimates indicate between 10% and 20% of all individuals with major depressive disorders (MDDs) fail to respond to conventional antidepressant therapies. Amongst those with MDD, individuals with treatment-resistant depression (TRD) have been found to be frequent users...
Persistent link: https://www.econbiz.de/10005404979
Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA). The antidepressant efficacy of mirtazapine has been established in randomised, double-blind comparative studies. Mirtazapine has generally shown similar efficacy to other antidepressants. There is evidence for a...
Persistent link: https://www.econbiz.de/10005405002
Objective: The aim of the present study is to describe a refinement of a previously presented method, based on the concept of point sensitivity, to deal with uncertainty in economic studies. Design: The original method was refined by the incorporation of probability distributions which allow a...
Persistent link: https://www.econbiz.de/10005405007