Background: As a direct result of the population growing older the total number of chronic illnesses increases. The future expenditure for care of chronically ill patients is an ever-present challenge for the health care system. New solutions based on integrated care or the inclusion of...

Healthcare problems are complex; they exhibit both detail and dynamic complexity. It has been argued that Discrete Event Simulation (DES), with its ability to capture detail, is ideal for problems exhibiting this type of complexity. On the other hand, System Dynamics (SD) with its focus on...

Uncertainty propagation of large-scale discrete supply chains can be prohibitive when numerous events occur during the simulated period and when discrete-event simulations (DES) are costly. We present a time-bucket method to approximate and accelerate the DES of supply chains. Its stochastic...

In practice, most projects result in cost overruns and schedule slippage due to poor resource management. This paper presents an approach that aims at reducing project duration and costs by empowering project managers to assess different scenarios. The proposed approach addresses combinatorial...

Background: Responding to the increasing demand for Deep Vein Thrombosis (DVT) treatment in the United Kingdom (UK) at times of limited budgets and resources is a great challenge for decision-makers. Therefore, there is a need to fnd innovative policies, which improve operational efciency and...

In every production plant, it is necessary to have an estimation of production level. Sometimes there are many parameters affective in this estimation. In this paper, it tried to find an appropriate estimation of production level for an industrial factory called Barez in an uncertain...

Purpose: Automobile terminals play an essential role in automotive supply chains. Due to short planning cycles and volatile planning information, the yard assignment determines terminals performance. Existing planning approaches are not able to cope with these dynamics. This contribution...