In population based genetic association studies, confounding due to population stratification (PS) arises when differences in both allele and disease frequencies exist in a population of mixed racial/ethnic subpopulations. Propensity scores are often used to address confounding in observational...

Two-stage predictor substitution (2SPS) and the two-stage residual inclusion (2SRI) are two approaches to instrumental variable (IV) analysis. While 2SPS and 2SRI with linear models are well-studied methods of causal inference, the properties of 2SPS and 2SRI for logistic binary outcomes have...

Two-stage predictor substitution (2SPS) and the two-stage residual inclusion (2SRI) are two approaches to instrumental variable (IV) analysis. While 2SPS and 2SRI with linear models are well-studied methods of causal inference, the properties of 2SPS and 2SRI for logistic binary outcomes have...

OBJECTIVE: We sought to determine whether lesbians have higher rates of overweight and obesity than women of other sexual orientations.METHODS: We compared population estimates of overweight and obesity across sexual orientation groups, using data from the 2002 National Survey of Family...

Background: Local Ontario Early Years Centres (OEYCs) collect timely and relevant local data, but knowledge translation is needed for the data to be useful. Maps represent an ideal tool to interpret local data. While geographic information system (GIS) technology is available, it is less clear...

Background: Organizations that collect substantial data for decision-making purposes are often characterized as being 'data rich' but 'information poor'. Maps and mapping tools can be very useful for research transfer in converting locally collected data into information. Challenges involved in...

Background: An important issue in prediction modeling of multivariate data is the measure of dependence structure. The use of Pearson's correlation as a dependence measure has several pitfalls and hence application of regression prediction models based on this correlation may not be an...

Background: In this paper we propose the use of the within-subject coefficient of variation as an index of a measurement's reliability. For continuous variables and based on its maximum likelihood estimation we derive a variance-stabilizing transformation and discuss confidence interval...