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Dynamic fitness landscapes: expansions for small mutation rates

Wilke, Claus O.; Ronnewinkel, Christopher - In: Physica A: Statistical Mechanics and its Applications 290 (2001) 3, pp. 475-490

We study the evolution of asexual microorganisms with small mutation rate in fluctuating environments, and develop techniques that allow us to expand the formal solution of the evolution equations to first order in the mutation rate. Our method can be applied to both discrete time and continuous...

Persistent link: https://www.econbiz.de/10010872872

Optimal adaptive performance and delocalization in NK fitness landscapes

Campos, Paulo R.A; Adami, Christoph; Wilke, Claus O - In: Physica A: Statistical Mechanics and its Applications 304 (2002) 3, pp. 495-506

We investigate the evolutionary dynamics of a finite population of sequences adapting to NK fitness landscapes. We find that, unlike in the case of an infinite population, the average fitness in a finite population is maximized at a small but finite, rather than vanishing, mutation rate. The...

Persistent link: https://www.econbiz.de/10010872601

Replication and Mutation on Neutral Networks

Reidys, Christian; Forst, Christian V.; Schuster, Peter - Santa Fe Institute - 1998

most of the evolutionarily relevant properties with them. <p> The theory of molecular quasispecies (in its simplest version … stochastic birth-and-death model. In analogy to the evolution of quasispecies in sequence space a phenotypic error threshold is … (ii) populations drifting through shape space in a diffusion-like process. The error classes of the quasispecies model are …

Persistent link: https://www.econbiz.de/10005790801