This paper deals with the organizational change in the provision of care for rare diseases, and the creation of a new structure: the centre of reference for rare diseases (CRMR). It aims to show that this new organization of care introduces a new authority within the healthcare organizational...

We evaluate the impact of cooperation with public research institutions on firms' inno-vative activities in France and Germany, using data from the fourth Community Innova-tion Survey (CIS4). We propose an original econometric methodology, which explicitly takes into account potential estimation...