We design a novel empirical framework to examine market efficiency through out-of-sample(OOS) predictability. We frame the classic empirical asset pricing problem as a machine learningclassification problem. We construct classification models to predict return states. The prediction- based...

We examine machine learning and factor-based portfolio optimization. We find that factors based on autoencoder neural networks exhibit a weaker relationship with commonly used characteristic-sorted portfolios than popular dimensionality reduction techniques. Machine learning methods also lead to...

We apply machine-learning techniques to predict drug approvals using drug-development and clinical-trial data from 2003 to 2015 involving several thousand drug-indication pairs with over 140 features across 15 disease groups. To deal with missing data, we use imputation methods that allow us to...

We find economically and statistically significant gains when using machine learning for portfolio allocation between the market index and risk-free asset. Optimal portfolio rules for time-varying expected returns and volatility are implemented with two Random Forest models. One model is...

This paper derives ex-ante (co)variances of stock-level and portfolio-level risk premium predictions from neural networks (NNs). Based on the precision of risk premium forecasts, I provide improved investment strategies. The confident high-low strategies that take long-short positions...

This paper introduces a new algorithm for exploiting time-series predictability-based patterns to obtain an abnormal return, or alpha, with respect to a given benchmark asset pricing model. The algorithm proposes a deterministic daily market timing strategy that decides between being fully...

We study whether large language models (LLMs) can generate suitable financial advice and which LLM features are associated with higher-quality advice. To this end, we elicit portfolio recommendations from 32 LLMs for 64 investor profiles, which differ in their risk preferences, home country,...

Nonlinear classification models can predict future earnings surprises with a high accuracy by using pricing and earnings input data. Surprises of 15% or more can be predicted with 71% accuracy. These predictions can be used to form profitable trading strategies. Additional variables have been...

In this tutorial we introduce recurrent neural networks (RNNs), and we describe the two most popular RNN architectures. These are the long short-term memory (LSTM) network and gated recurrent unit (GRU) network. Their common field of application is time series modeling, and we demonstrate their...

This paper identiftes U.S. monetary and ftscal dominance regimes using machine learning techniques. The algorithms are trained and verifted by employing simulated data from Markov-switching DSGE models, before they classify regimes from 1968-2017 using actual U.S. data. All machine learning...