The detection of a change from a constant level to a monotonically increasing (or decreasing) regression is of special interest for the detection of outbreaks of, for example, epidemics. A maximum likelihood ratio statistic for the sequential surveillance of an “outbreak” situation is...

Outbreak detection is of interest for several diseases and syndromes. The aim is to detect the progressing increase in the incidence as soon as possible after the onset of the outbreak. A semiparametric method is applied to Swedish data on tularemia and influenza. The method is constructed to...

On-line monitoring is needed to detect outbreaks of diseases like influenza. Surveillance is also needed for other kinds of outbreaks, in the sense of an increasing expected value after a constant period. Information on spatial location or other variables might be available and may be utilized....