Prior marketing literature has overlooked the role of regulatory regimes in explaining international sales growth of new products. This paper addresses this gap in the context of new pharmaceuticals (15 new molecules in 34 countries) and sheds light on the effect regulatory regimes have on new...

Implicit in the drug-approval process is a host of decisions---target patient population, control group, primary endpoint, sample size, follow-up period, etc.---all of which determine the trade-off between Type I and Type II error. We explore the application of Bayesian decision analysis (BDA)...

During the recent COVID-19 pandemic crisis, several high-income countries pursued vaccine nationalism (i.e., my country first approaches for vaccine distribution), leading to an even wider income inequality between rich and poor countries. This significantly challenged the poorer countries'...

Due to differences in the effectiveness and side effects of different drugs, uncertainty is an important component of prescription drug choice. This uncertainty can cause patients and doctors to experiment with different drugs until they find a good match. In this paper, we specify and estimate...

We analyze the impact of public health policy on the spread of a disease using a version of the SIR model that includes vital statistics, waning immunity, and vaccination. This model is rich enough to accommodate endemic steady states and disease-free steady states. We choose social distancing...

In many countries, the COVID-19 vaccination program faces great challenges, from the management of limited and irregular supply of vaccines, uncertain vaccine take-up rate from the population, and appropriate appointment booking management to reduce congestion etc. In addition, the feature of a...

The paper uses a real option approach to investigate the impact of performance-based risk-sharing agreements for the reimbursement of new drugs in comparison with standard cost-effectiveness thresholds. The results show that the exact definition of the risk-sharing agreement is key in...

Medicare Part D provides prescription drug coverage through Medicare approved plans offered by private insurance companies and HMOs. In this paper, we study the role of current prescription drug use and health risks, related expectations, and subjective factors in the demand for prescription...

This paper evaluates the cost-effectiveness of vaccinating women against human papillomaviruses (HPV) in the Czech Republic, where HPV is the main cause of most cervical carcinomas. It examines the cost-effectiveness of the current reimbursement policy for HPV vaccination compared to the...

Research on the launch of new products in the international realm is scarce. The present paper is the first to document how launch window (difference in months between the first worldwide launch and the subsequent launch in a specific country) and launch price are interrelated and how regulation...