Heo, Moonseong; Xue, Xiaonan; Kim, Mimi Y. - In: Computational Statistics & Data Analysis 60 (2013) C, pp. 169-178
In longitudinal cluster randomized clinical trials (cluster-RCT), subjects are nested within a higher level unit such as clinics and are evaluated for outcome repeatedly over the study period. This study design results in a three level hierarchical data structure. When the primary goal is to...