Pharmacoeconomic analyses have become useful and essential tools for health care decision makers who increasingly require such analyses prior to placing a drug on a national, regional or hospital formulary. Previous health economic models of non-steroidal anti-inflammatory drugs (NSAIDs) have...

To complement the evidence-based practice paradigm, the authors argued for a core outcome measure to provide practice-based evidence for the psychological therapies. Utility requires instruments that are acceptable scientifically, as well as to service users, and a coordinated implementation of...

This thesis contrasts vaccine innovation efforts in the cases of poliomyelitis and HIV/AIDS. It addresses the question of why some fields of human endeavour can be seen to yield positive change more quickly than others. The thesis develops a perspective that views innovation as a cumulative...