"This book offers the latest the field has to offer to practitioners and academics alike, presented through theoretical frameworks, case studies, and future directions by providing current, current edge and provocative scientific work in the three domains of pharmacoinformatics: decision making...

Policy makers need reliable estimates of direct costs of pharmaceutical R&D, in order to contain health-care costs and at the same time maintain a supportive environment for investment in research. This paper evaluates the application of parametric estimating methods to the late stage clinical...

We examine the role of spillover learning in shaping the value of exploratory versus incremental R&D. Using data from drug development, we show that novel drug candidates generate more knowledge spillovers than incremental ones. Despite being less likely to reach regulatory approval, they are...