Kakushadze, Zura; Yu, Willie - 2017
://ssrn.com/abstract=2908286) to 10,656 published exome samples for 32 cancer types. A majority of cancer types exhibit mutation clustering … across 14 cancer types. In contrast, we find in- and out-of-sample instabilities in cancer signatures extracted from exome …-stage cancer diagnostics such as novel blood-test methods currently in development …
