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We examine the role of spillover learning in shaping the value of exploratory versus incremental R&D. Using data from drug development, we show that novel drug candidates generate more knowledge spillovers than incremental ones. Despite being less likely to reach regulatory approval, they are...
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tropical diseases prevalent in low-income settings. The growing gap between the need for new pharmaceuticals and their …-promoting pharmaceuticals. Over the past three decades, prior reforms based on using these levers to incentivize drug development have been … innovation has both benefits and substantial problems for public health, including negative consequences for the patients these …
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In October 2002, a substitution reform was introduced in the Swedish pharmaceuticals market. In this paper, the effects …
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Policy makers need reliable estimates of direct costs of pharmaceutical R&D, in order to contain health-care costs and at the same time maintain a supportive environment for investment in research. This paper evaluates the application of parametric estimating methods to the late stage clinical...
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These are neither the best of times nor the worst of times for the pharmaceutical industry, or for global public health. Media reports regarding recent legal developments would suggest that the originator pharmaceutical industry is facing a new and dangerous threat to its long-term welfare,...
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, particularly from an economic standpoint. In this regard, pharmaceuticals are not generally traded in what might be described as a … because it is imported. Parallel trade (i.e., imports and exports) in pharmaceuticals takes place in markets that are … international exhaustion. This should help to facilitate price reductions in the global market for pharmaceuticals …
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