This study analyzes the effect of economies of scale and scope on the optimal case mix of a hospital or hospital system. With respect to the ideal volume and patient composition, the goal is to evaluate (i) the impact of changes in the efficiency of resource use with increasing scale, and (ii)...

Coordinated services and virtual medicine are the two innovative concepts being employed in the transformation from provider-centered care to patient-centered care. In this paper, we combine these two concepts to study a coordinated scheduling problem with both virtual medicine patients (VM...

Strong liquefied natural gas (LNG) demand growth, especially in Asia, could increasingly motivate gas infrastructure development in North America. Nevertheless, opposition to new gas infrastructure is formidable in some of the U.S. states and Canadian provinces that are well positioned to supply...

Market equilibrium models are often specified and solved as mixed complementarity problems (MCPs). These formulations combine the Karush-Kuhn-Tucker (KKT) optimality conditions of the optimization problems faced by multiple strategic players with market-clearing conditions, such that the...

The first objective of this book is to provide an up-to-date exposition of the techniques that are available for optimizing complex systems and to do so in a way that unifies the theory of nondifferentiable and two-level mathematical programming. The second objective is to highlight the most...